Nationwide Children Kidney and Urinary Tract Symposium State of the Art in Pediatric UTI 2025

• Target Audience: pediatricians, nephrologists, urologists, infectious disease specialists, and primary care providers
• Sample video: contact me for sample video
• Information:

Target Audience: Specialties – General Pediatrics, Infectious Diseases, Nephrology, Urology

Overview

The overall goal of this fourth annual symposium is to provide a current, high-level summary of the state-of-the-art regarding mechanisms and management of pediatric UTI. A panel of experts will highlight knowledge gaps and making recommendations about next steps for research to guide the care of patients with UTI. This includes the role for host-pathogen interactions in UTI pathogenesis; host defense mechanisms to prevent and eradicate UTI; urologic evaluation of patients with recurrent UTI; antibiotic prophylaxis in UTI prevention; and the impact of recurrent UTI on the kidney. Facilitated discussions will provide opportunities to gather patient and caregiver perspectives and identify research opportunities and priorities, to achieve the best future for children with UTI.

Objectives

At the conclusion of this activity, learners will be able to:

Describe mechanisms of urinary tract infection (UTI) pathogenesis

Utilize emerging measures to prevent and treat UTI

Implement the latest clinical approaches to UTI diagnosis, treatment and prevention

Reduce the impact of UTI on patients and caregivers by implementing new strategies.

Improve communication and collaboration with the healthcare team.

• Topics:

*Note: these are continuous video recordings during the conference, they include individual lectures mentioned in the Detail section below

Feb 21.mp4 (8 hours)

Antibiotic Prophylaxis for UTI.pdf

Innate defenses in UTI- Interleukin-6 impacts urothelial immunity.pdf

Understanding UTIs Immune Mechanisms, Models, and Therapies Across the Lifespan.pdf

UTI and Epithelial Immunity.pdf

UTI Pathogens, Epidemiology, and Resistance.pdf

Why Do We Care About UTI.pdf

* Detail:

Friday, February 21, 2025

Welcome and Introductions

Why Do We Care About UTI

Nader Shaikh, MD, MPH

UTI Pathogens, Epidemiology, and Resistance

Laura A Mike, PhD

A Mouse Model of Acquired Renal Scarring after UTI

Denise Kimbrough, MD PhD

Break

Understanding UTIs: Immune Mechanisms, Models, and Therapies Across the Lifespan

Indira Mysorekar, PhD, FAAM

Antibiotic Prophylaxis for UTI

David Hains, MD, MBA

Lunch

Innate defenses in UTI: Interleukin-6 impacts urothelial immunity

Christina Ching, MD

SUPER Lightning Presentations

Characterization of UTI Defenses in Diabetic, Obese ob/ob Mice

Natalia Cuyler

Point Reyes, CAEnhancing Antimicrobial Functions in Neutrophils to Combat Urinary Tract Infections

Josh Putka

Avon, OH

Impact of Uropathogenic Escherichia coli on the mTOR Signaling Pathway

Vanessa Arias

Garfield, NJ

UTI Treatment and NCH UTI Pathway

Joshua Watson, MD

Break

Urologic Evaluation of rUTI

Luis Braga, MD, MSc, PhD

Unveiling Biomarkers and Mechanistic Pathways in Acute Pyelonephritis Through a Spatio-Temporal Transcriptome Atlas

Juan de Dios Ruiz Rosado, PhD