USCAP Don’t Go Down the Tubes Updates in the Diagnosis of Luminal Gastrointestinal Neoplasia 2025

• Include:  videos +  pdf, size:  GB
• Target Audience: pathologists, gastrointestinal subspecialists, fellows, trainees
• Sample video: contact me for sample video
• Information:

Original release date: November 12, 2025

Target Audience

Practicing academic and community pathologists, and pathologists-in-training

Learning Objectives

Upon completion of this educational activity, learners will be able to:

Describe, diagnose, and properly classify luminal neoplasia throughout the GI tract.

Discuss and evaluate precursor lesions and histologic criteria associated with progression.

Recognize essential syndromic associations and clinically relevant molecular abnormalities.

Distinguish entities in differential diagnosis and important mimics of luminal GI neoplasms.

Who Should Attend

Practicing surgical pathologists who routinely diagnose GI biopsies and resections

GI subspecialty pathologists seeking updates on evolving diagnostic criteria

Residents and fellows in pathology preparing for boards or subspecialty training

Academic clinicians and researchers interested in translational aspects of GI neoplasia

Oncology teams and multidisciplinary clinicians who rely on accurate pathology for patient management

What You’ll Learn

This USCAP short course emphasizes practical diagnostic challenges and updates in luminal GI pathology. Key highlights include:

Refinements in diagnostic criteria for adenomas, adenocarcinomas, and serrated lesions

Updates on molecular pathology and its role in classification and prognosis

Pitfalls and pearls in distinguishing reactive changes from neoplasia

Case-based discussions with expert faculty to sharpen interpretive skills

Integration of histology, immunohistochemistry, and molecular tools for accurate diagnosis

• Topics:

Intestinal Polyps and Adenocarcinoma – Alexandros D. Polydorides, MD, PhD

Assorted Mesenchymal Cases in All Lineages – Elizabeth E. Montgomery, MD

Gastric Polyps – Gregory Y. Lauwers, MD

Esophageal Carcinoma and Precursors – Nicole C. Panarelli, MD

Appendiceal and Anal Neoplasia – Alexandros D. Polydorides, MD, PhD

GIST and Other Matters – Elizabeth E. Montgomery, MD

Gastric Metaplasia, Dysplasia, Carcinoma – Gregory Y. Lauwers, MD

Neuroendocrine Neoplasms – Nicole D. Panarelli, MD